Linerase collagen biostimulator launches in Malaysia

Linerase, the advanced collagen biostimulator developed by Italian company, CSD, has launched in Malaysia. Designed to stimulate the body's natural collagen production, Linerase offers a revolutionary approach to skin rejuvenation, restoring elasticity, firmness, and youthful radiance through scientifically backed biostimulation. The product is distributed by Venusys Medical.

(From left) Dr. Lim Ting Song, aesthetic physician and medical director at Clique Clinic; Dr. Katerina Gkouvi, dermatologist from Greece; Professor Andrea Corbo, Founder of Linerase and dermatologist from Italy; Mr Carlo Berardini, General Manager of Linerase

During the launch event, international expert Professor Andrea Corbo, Founder of Linerase and dermatologist from Italy and Dr. Katerina Gkouvi, dermatologist from Greece shared insights into the science behind Linerase and its unique applications. The program concluded with Dr Lim Ting Song, aesthetic physician and medical director at Clique Clinic presenting results from local clinical trials, highlighting significant improvements in skin quality, elasticity, and resilience following treatment with Linerase.

Science behind Linerase

Unlike traditional treatments that add volume or temporarily mask aging, Linerase directly targets the fibroblasts of our skin, which are essentially the cells that act as collagen factories within the skin. Upon being exposed to Linerase, these fibroblasts are stimulated to multiply themselves. Furthermore, Linerase also provides amino acids to these newly-formed fibroblasts, which are utilized as raw materials in the formation of new collagen. All of these effects work in tandem to significantly enhance the production of Type III collagen within our skin. This process helps restore skin firmness, improve texture, and support long-term skin regeneration. Its key indications include:

• - Restoring skin elasticity and firmness in the face, neck, décolletage, and other body areas
• - Improving atrophic skin conditions such as stretch marks, acne scars, post-surgical scars, and trauma lesions

Formulated with Heterologous Type I Collagen (HTIC) derived from equine sources, Linerase breaks down into amino acids and tripeptides upon hydrolysis. The tripeptides stimulate the formation of new fibroblasts and inhibit collagen-degrading enzymes, while the amino acids support the production of Type III collagen. This results in exceptional biocompatibility, promotes effective wound healing, and supports dermo-epidermal regeneration — all while maintaining a strong safety profile with no reported immune responses to date.

Linerase stands out in the field of regenerative aesthetics by stimulating the production of Type III collagen — a critical component in tissue repair, skin elasticity, and neovascularization. Its uniquely low molecular weight formulation (under 1 kiloDalton) significantly reduces the risk of allergenic reactions and granuloma formation, remaining well below the 10 kiloDalton threshold typically associated with such responses. Unlike many collagen stimulators that primarily target Type I collagen — which can lead to thicker, more fibrotic tissue — Linerase promotes the regeneration of Type III collagen, closely associated with youthful, resilient skin. This targeted approach results in more natural, supple outcomes, reinforcing Linerase's position as a safer and more advanced solution in aesthetic medicine.

"At Linerase, we believe that true skin rejuvenation lies not in covering up imperfections but in restoring the skin's natural structure and vitality. With Linerase, we are empowering the skin to heal, regenerate, and reveal its healthiest state," said Prof. Andrea Corbo during his sharing session.

Echoing this sentiment, Dr. Katerina shared, "Linerase fills an important gap in modern aesthetic medicine — offering patients a treatment that not only addresses visible signs of aging but does so in a way that is safe, natural, and scientifically backed. It's a new chapter for skin health in Malaysia."

Backed by over 30 years of research from its Italian developer CSD, and certified with ISO 9001 and ISO 13485 standards, Linerase stands at the forefront of regenerative aesthetics. Its scientifically proven efficacy, biocompatibility, and long-lasting natural results set a new benchmark in non-invasive skin rejuvenation.

About LINERASE

Linerase is a collagen biostimulator treatment developed by CSD, an Italian company founded in 1997 with a strong heritage in science, research, and aesthetic medicine. Certified with ISO 9001 and ISO 13485, CSD has dedicated the last three decades to advancing dermal biorevitalization technologies, specializing in innovative formulations using native Type I Collagen.

At the heart of Linerase is a commitment to slowing down the aging process by naturally regenerating the skin's structure, improving firmness, texture, and radiance. Designed to repair and reverse visible signs of skin aging, Linerase offers a cutting-edge approach to aesthetic treatments by stimulating the body's own collagen production.

About Venusys Medical

Venusys Medical was incorporated since 2005. The company has since been the pioneer in the distribution of laser, light-based equipment and other multi-technology systems for the aesthetic and surgical markets. Its medical equipment are registered and approved by the Ministry of Health Malaysia to meet the stringent demand of the medical industry. Its portfolio focuses on two divisions – Aesthetic equipment and life science research products.