Lesaffre Human Care, supplier of quality ingredients from yeast and bacteria fermentation for the global human care markets, has announced the publication of two scientific papers[i],[ii] on the beneficial effects of S. cerevisiae-based ingredients on women’s health:
- in the Medical Journal of Obstetrics and Gynecology: https://www.jscimedcentral.com/Obstetrics/obstetrics-5-1112.pdf
- in Beneficial Microbes> http://www.wageningenacademic.com/doi/pdf/10.3920/BM2017.0099.
The two publications show continuous recognition from the scientific community of the company’s long-term investment in providing strong scientific and clinical data to substantiate the unique health benefits of its ingredients. For example, research supporting the positive effects of the company’s exclusive S. cerevisiae-based ingredients in women health has been published in several peer-reviewed journals[iii],[iv] and presented at industry-events and international conferences on numerous occasions since 2016.
To further their knowledge of S. cerevisiae CNCM I-3856 benefits on women’s intimate health, the company launched a clinical study to find out the effects of oral administration of this probiotic[v] yeast as an adjuvant therapy in women suffering from vulvovaginal candidiasis (VVC). Results, which spearheaded the publication in the Medical Journal of Obstetrics and Gynecology1 of one of the new scientific papers, showed that probiotic yeast S. cerevisiae CNCM I-3856 is “easy-to-use and well tolerated” and that “the probiotic yeast is efficient in controlling vaginal Candida proliferation after conventional treatment thus limiting VVC recurrence”.
In addition to these findings, the peer-reviewed paper published in Beneficial Microbes2 this February revealed promising anti-fungal and anti-inflammatory properties for vaginal candidiasis therapy. Researchers concluded that “the beneficial effect exerted by this S. cerevisiae-based probiotic is the result of its interference with the expression of fungus virulence factors coupled with the modulation of the inflammatory response of the host”.
All of these new discoveries strengthen previous research results on Lesaffre Human Care’s S. cerevisiae-based ingredients for women health enhancement and prompt the company to keep investing in clinical research to reveal the full potential of each and every one of its health-promoting ingredients.
[i] Cayzeele-Decherf A, Pélerin F, Jüsten P (2017) Saccharomyces cerevisiae CNCM I-3856 as a Natural Breakthrough for Vaginal Health: A Clinical Study. Med J Obstet Gynecol 5(4): 1112. https://www.jscimedcentral.com/Obstetrics/obstetrics-5-1112.pdf
[ii] E. Gabrielli, E. Pericolini, N. Ballet, E. Roselletti, S. Sabbatini, P. Mosci, A. Cayzeele Decherf, F. Pélerin, S. Perito, P. Jüsten & A. Vecchiarelli (2018) Saccharomyces cerevisiae-based probiotic as novel anti-fungal and anti-inflammatory agent for therapy of vaginal candidiasis. Beneficial Microbes 2018 9(2): 219-230. http://www.wageningenacademic.com/doi/pdf/10.3920/BM2017.0099
[iii] Wilson D, A tale of two yeasts: Saccharomyces cerevisiae as a therapeutic against candidiasis. 2016, Virulence 31:1-3.
[iv] Pericolini E, Gabriellini E, Ballet N, Sabbatini S, Roselletti E, Cayzeele Decherf A, Pélerin F, Luciano E, Perito S, Jüsten P & Vecchiarelli A. Therapeutic activity of Saccharomyces cerevisiae-based probiotic and inactivated whole yeast on vaginal candidiasis. 2016, Virulence 19:1-17.
[v] The World Health Organization defines probiotics as "live micro-organisms which, when administered in adequate amounts, confer a health benefit on the host."
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